2HC4

Crystal structure of the LBD of VDR of Danio rerio in complex with calcitriol

Summary for 2HC4

Entry DOI	10.2210/pdb2hc4/pdb
Related	1DB1 2HBH 2HCD
Descriptor	Vitamin D receptor, SRC-1 from Nuclear receptor coactivator 1, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	alpha helical sandwich, gene regulation
Biological source	Danio rerio (zebrafish) More
Cellular location	Nucleus: Q9PTN2 Nucleus (By similarity): Q15788
Total number of polymer chains	2
Total formula weight	36253.38
Authors	Ciesielski, F.,Rochel, N.,Moras, D. (deposition date: 2006-06-15, release date: 2007-05-01, Last modification date: 2023-10-25)
Primary citation	Ciesielski, F.,Rochel, N.,Moras, D. Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: remodelling the LBP with one side chain rotation J.Steroid Biochem.Mol.Biol., 103:235-242, 2007 Cited by PubMed: 17218092 DOI: 10.1016/j.jsbmb.2006.12.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation