2HBM

Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain; Protein in complex with Mn, Zn, and UMP

2HBM の概要

• エントリーDOI: 10.2210/pdb2hbm/pdb
• 関連するPDBエントリー: 2HBJ 2HBK 2HBL
• 分子名称: Exosome complex exonuclease RRP6, ZINC ION, MANGANESE (II) ION, ... (5 entities in total)
• 機能のキーワード: exosome, rna metabolism, rna surveillance, rna processing, hydrolase, gene regulation
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast)
• 細胞内の位置: Nucleus, nucleolus : Q12149
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48119.65

構造登録者

Midtgaard, S.F.,Assenholt, J.,Jonstrup, A.T.,Van, L.B.,Jensen, T.H.,Brodersen, D.E. (登録日: 2006-06-14, 公開日: 2006-07-25, 最終更新日: 2024-05-29)

• 主引用文献: Midtgaard, S.F.,Assenholt, J.,Jonstrup, A.T.,Van, L.B.,Jensen, T.H.,Brodersen, D.E.; Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain.; Proc.Natl.Acad.Sci.Usa, 103:11898-11903, 2006; PubMed: 16882719; DOI: 10.1073/pnas.0604731103

実験手法

X-RAY DIFFRACTION (2.7 Å)