2H9R

Docking and dimerization domain (D/D) of the regulatory subunit of the Type II-alpha cAMP-dependent protein kinase A associated with a Peptide derived from an A-kinase anchoring protein (AKAP)

2H9R の概要

• エントリーDOI: 10.2210/pdb2h9r/pdb
• 関連するPDBエントリー: 1L6E 1R2A 2DRN 2HWN
• 分子名称: cAMP-dependent protein kinase type II-alpha regulatory subunit, 22-mer from A-kinase anchor protein 5 (2 entities in total)
• 機能のキーワード: akap, pka, signal transduction, 4-helix bundle, helix-loop-helix, protein-peptide complex, transferase
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• 細胞内の位置: Membrane: P24588
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 13180.16

構造登録者

Newlon, M.G.,Roy, M.,Morikis, D.,Hausken, Z.E.,Coghlan, V.,Scott, J.D.,Jennings, P.A. (登録日: 2006-06-10, 公開日: 2006-08-29, 最終更新日: 2022-03-09)

• 主引用文献: Newlon, M.G.,Roy, M.,Morikis, D.,Carr, D.W.,Westphal, R.,Scott, J.D.,Jennings, P.A.; A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes.; Embo J., 20:1651-1662, 2001; PubMed: 11285229; DOI: 10.1093/emboj/20.7.1651

実験手法

SOLUTION NMR