2H6P

Crystal structure of HLA-B*3501 presenting the human cytochrome P450 derived peptide, KPIVVLHGY

2H6P の概要

• エントリーDOI: 10.2210/pdb2h6p/pdb
• 分子名称: HLA-B35, Beta-2-microglobulin, 9 mer peptide from Cytochrome P450, ... (4 entities in total)
• 機能のキーワード: immune system, gene regulation
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P61769; Endoplasmic reticulum membrane; Peripheral membrane protein: P33260
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44715.67

構造登録者

Archbold, J.K.,Macdonald, W.A.,Rossjohn, J. (登録日: 2006-05-31, 公開日: 2006-09-19, 最終更新日: 2011-07-13)

• 主引用文献: Archbold, J.K.,Macdonald, W.A.,Miles, J.J.,Brennan, R.M.,Kjer-Nielsen, L.,McCluskey, J.,Burrows, S.R.,Rossjohn, J.; Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry; J.Biol.Chem., 281:34324-34332, 2006; PubMed: 16963442; DOI: 10.1074/jbc.M606755200

実験手法

X-RAY DIFFRACTION (1.9 Å)