2H5C

0.82A resolution crystal structure of alpha-lytic protease at pH 5

2H5C の概要

• エントリーDOI: 10.2210/pdb2h5c/pdb
• 関連するPDBエントリー: 1QRX 1SSX 1TAL 2H5D 2ULL
• 分子名称: ALPHA-LYTIC PROTEASE, SULFATE ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: a-lytic protease, serine protease, acylation transition state, catalysis, protein folding, protein stability, packing distortion, hydrolase
• 由来する生物種: Lysobacter enzymogenes
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21116.01

構造登録者

Fuhrmann, C.N.,Daugherty, M.D.,Agard, D.A. (登録日: 2006-05-25, 公開日: 2006-09-26, 最終更新日: 2023-08-30)

• 主引用文献: Fuhrmann, C.N.,Daugherty, M.D.,Agard, D.A.; Subangstrom crystallography reveals that short ionic hydrogen bonds, and not a His-Asp low-barrier hydrogen bond, stabilize the transition state in serine protease catalysis; J.Am.Chem.Soc., 128:9086-9102, 2006; PubMed: 16834383; DOI: 10.1021/ja057721o

実験手法

X-RAY DIFFRACTION (0.82 Å)