2H2B

Crystal Structure of ZO-1 PDZ1 Bound to a Phage-Derived Ligand (WRRTTYL)

2H2B の概要

• エントリーDOI: 10.2210/pdb2h2b/pdb
• 関連するPDBエントリー: 2H2C 2H3L 2H3M
• 分子名称: Tight junction protein ZO-1, ACETIC ACID (3 entities in total)
• 機能のキーワード: pdz domain, phage derived high affinity ligand, cell adhesion
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q07157
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11776.29

構造登録者

Appleton, B.A.,Zhang, Y.,Wu, P.,Yin, J.P.,Hunziker, W.,Skelton, N.J.,Sidhu, S.S.,Wiesmann, C. (登録日: 2006-05-18, 公開日: 2006-06-13, 最終更新日: 2023-08-30)

• 主引用文献: Appleton, B.A.,Zhang, Y.,Wu, P.,Yin, J.P.,Hunziker, W.,Skelton, N.J.,Sidhu, S.S.,Wiesmann, C.; Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity.; J.Biol.Chem., 281:22312-22320, 2006; PubMed: 16737969; DOI: 10.1074/jbc.M602901200

実験手法

X-RAY DIFFRACTION (1.6 Å)