2H24

Crystal structure of human IL-10

Summary for 2H24

• Entry DOI: 10.2210/pdb2h24/pdb
• Related: 1INR
• Descriptor: Interleukin-10 (2 entities in total)
• Functional Keywords: alpha-helix bundle, cytokine
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P22301
• Total number of polymer chains: 1
• Total formula weight: 18672.45

Authors

Yoon, S.I.,Walter, M.R. (deposition date: 2006-05-18, release date: 2006-10-17, Last modification date: 2023-08-30)

• Primary citation: Yoon, S.I.,Logsdon, N.J.,Sheikh, F.,Donnelly, R.P.,Walter, M.R.; Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex.; J.Biol.Chem., 281:35088-35096, 2006; PubMed: 16982608; DOI: 10.1074/jbc.M606791200

Experimental method

X-RAY DIFFRACTION (2 Å)