2H03
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
Summary for 2H03
Entry DOI | 10.2210/pdb2h03/pdb |
Related | 2HO2 2HO4 |
Descriptor | Protein tyrosine phosphatase, receptor type, B,, CHLORIDE ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | protein tyrosine phosphatase, wpd-loop, sulfamic acid, phosphatase, inhibitor, drug design, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 34388.41 |
Authors | Evdokimov, A.G.,Pokross, M.E.,Walter, R.L.,Mekel, M.,Gray, J.L.,Peters, K.G.,Maier, M.B.,Amarasinghe, K.D.,Clark, C.M.,Nichols, R. (deposition date: 2006-05-13, release date: 2006-06-13, Last modification date: 2023-08-30) |
Primary citation | Amarasinghe, K.K.,Evdokimov, A.G.,Xu, K.,Clark, C.M.,Maier, M.B.,Srivastava, A.,Colson, A.O.,Gerwe, G.S.,Stake, G.E.,Howard, B.W.,Pokross, M.E.,Gray, J.L.,Peters, K.G. Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta. Bioorg.Med.Chem.Lett., 16:4252-4256, 2006 Cited by PubMed: 16759857DOI: 10.1016/j.bmcl.2006.05.074 PDB entries with the same primary citation |
Experimental method |
Structure validation
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