2GZA

Crystal structure of the VirB11 ATPase from the Brucella Suis type IV secretion system in complex with sulphate

2GZA の概要

• エントリーDOI: 10.2210/pdb2gza/pdb
• 分子名称: Type IV secretion system protein VirB11, SULFATE ION (3 entities in total)
• 機能のキーワード: secretion, atpase, hydrolase
• 由来する生物種: Brucella suis
• 細胞内の位置: Cytoplasm : Q8FXK7
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 122626.87

構造登録者

Hare, S.,Bayliss, R.,Baron, C.,Waksman, G. (登録日: 2006-05-11, 公開日: 2006-07-11, 最終更新日: 2023-08-30)

主引用文献

Hare, S.,Bayliss, R.,Baron, C.,Waksman, G.
A Large Domain Swap in the VirB11 ATPase of Brucella suis Leaves the Hexameric Assembly Intact
J.Mol.Biol., 360:56-66, 2006

PubMed Abstract: VirB11 ATPases are hexameric assemblies that power type IV secretion systems in bacteria. The hexamer of Brucella suis VirB11 (BsB11), like that of the Helicobacter pylori VirB11 (Hp0525), consists of a double ring structure formed by the N-terminal and C-terminal domains of each monomer. However, the monomer differs dramatically from that of Hp0525 by a large domain swap that leaves the hexameric assembly intact but profoundly alters the nucleotide-binding site and the interface between subunits.

PubMed: 16730027
DOI: 10.1016/j.jmb.2006.04.060

実験手法

X-RAY DIFFRACTION (2.6 Å)