2GWA

Crystal Structure of a Complex Formed Between the DNA Holliday Junction and a Bis-Acridine Molecule.

Summary for 2GWA

• Entry DOI: 10.2210/pdb2gwa/pdb
• Related: 2GB9
• Descriptor: 5'-D(*Tp*Cp*Gp*Gp*Tp*Ap*Cp*Cp*Gp*A)-3', 9,9'-(HEXANE-1,6-DIYLDIIMINO)BIS{N-[2-(DIMETHYLAMINO)ETHYL]ACRIDINE-4-CARBOXAMIDE}, SPERMINE, ... (4 entities in total)
• Functional Keywords: dna holliday junction bis-acridine, dna
• Total number of polymer chains: 2
• Total formula weight: 6991.25

Authors

Brogden, A.L.,Hopcroft, N.H.,Cardin, C.J.,Searcey, M. (deposition date: 2006-05-04, release date: 2006-06-06, Last modification date: 2023-08-30)

• Primary citation: Brogden, A.L.,Hopcroft, N.H.,Searcey, M.,Cardin, C.J.; Ligand bridging of the DNA Holliday junction: molecular recognition of a stacked-X four-way junction by a small molecule.; Angew.Chem.Int.Ed.Engl., 46:3850-3854, 2007; PubMed: 17477457; DOI: 10.1002/anie.200603760

Experimental method

X-RAY DIFFRACTION (1.75 Å)