2GVG
Crystal Structure of human NMPRTase and its complex with NMN
Summary for 2GVG
Entry DOI | 10.2210/pdb2gvg/pdb |
Related | 2GVJ |
Descriptor | Nicotinamide phosphoribosyltransferase, PHOSPHATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, ... (4 entities in total) |
Functional Keywords | nmprtase, visfatin, pbef, crystal, cancer, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): P43490 |
Total number of polymer chains | 6 |
Total formula weight | 336720.64 |
Authors | Khan, J.A.,Tao, X.,Tong, L. (deposition date: 2006-05-02, release date: 2006-06-20, Last modification date: 2024-02-14) |
Primary citation | Khan, J.A.,Tao, X.,Tong, L. Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat.Struct.Mol.Biol., 13:582-588, 2006 Cited by PubMed: 16783377DOI: 10.1038/nsmb1105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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