2GV2

MDM2 in complex with an 8-mer p53 peptide analogue

Summary for 2GV2

Entry DOI	10.2210/pdb2gv2/pdb
Related	1RV1 1T4E 1T4F 1YCR
Descriptor	E3 ubiquitin-protein ligase Mdm2, 8-MER P53 PEPTIDE ANALOGUE (3 entities in total)
Functional Keywords	optimized protein-protein interaction. synthetic peptide. alpha helix binding protein, ligase
Biological source	Homo sapiens (human) More
Cellular location	Nucleus, nucleoplasm: Q00987
Total number of polymer chains	2
Total formula weight	13787.12
Authors	Schubert, C.,Sakurai, K. (deposition date: 2006-05-02, release date: 2006-09-05, Last modification date: 2023-11-15)
Primary citation	Sakurai, K.,Schubert, C.,Kahne, D. Crystallographic Analysis of an 8-mer p53 Peptide Analogue Complexed with MDM2. J.Am.Chem.Soc., 128:11000-11001, 2006 Cited by PubMed: 16925398 DOI: 10.1021/ja063102j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation