2GTP

Crystal structure of the heterodimeric complex of human RGS1 and activated Gi alpha 1

2GTP の概要

• エントリーDOI: 10.2210/pdb2gtp/pdb
• 分子名称: Guanine nucleotide-binding protein G(i), alpha-1 subunit, Regulator of G-protein signaling 1, TETRAFLUOROALUMINATE ION, ... (6 entities in total)
• 機能のキーワード: g protein signalling, rgs, heterotrimeric g protein, signalling complex, structural genomics, structural genomics consortium, sgc, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus (By similarity): P63096
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 108354.99

構造登録者

Soundararajan, M.,Turnbull, A.P.,Ugochukwu, E.,Gorrec, F.,von Delft, F.,Weigelt, J.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,Doyle, D.A.,Structural Genomics Consortium (SGC) (登録日: 2006-04-28, 公開日: 2006-05-23, 最終更新日: 2023-08-30)

• 主引用文献: Soundararajan, M.,Willard, F.S.,Kimple, A.J.,Turnbull, A.P.,Ball, L.J.,Schoch, G.A.,Gileadi, C.,Fedorov, O.Y.,Dowler, E.F.,Higman, V.A.,Hutsell, S.Q.,Sundstrom, M.,Doyle, D.A.,Siderovski, D.P.; Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.; Proc.Natl.Acad.Sci.Usa, 105:6457-6462, 2008; PubMed: 18434541; DOI: 10.1073/pnas.0801508105

実験手法

X-RAY DIFFRACTION (2.55 Å)