2GS4

The crystal structure of the E.coli stress protein YciF.

2GS4 の概要

• エントリーDOI: 10.2210/pdb2gs4/pdb
• 分子名称: Protein yciF (2 entities in total)
• 機能のキーワード: stress proteins, rubrerythrin, metal binding protein
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37625.51

構造登録者

Hindupur, A.,Liu, D.,Zhao, Y.,Bellamy, H.D.,White, M.A.,Fox, R.O. (登録日: 2006-04-25, 公開日: 2006-10-17, 最終更新日: 2024-10-30)

主引用文献

Hindupur, A.,Liu, D.,Zhao, Y.,Bellamy, H.D.,White, M.A.,Fox, R.O.
The crystal structure of the E. coli stress protein YciF.
Protein Sci., 15:2605-2611, 2006

PubMed Abstract: YciF is a protein that is up-regulated when bacteria experience stress conditions, and is highly conserved in a range of bacterial species. YciF has no known structure or biochemical function. To learn more about its potential molecular function and its role in the bacterial stress response, we solved the crystal structure of YciF at 2.0 Angstrom resolution by the multiple wavelength anomalous diffraction (MAD) technique. YciF is a dimer in solution, and forms a homodimer in the crystal asymmetric unit. The two monomers form a dimer with a molecular twofold axis, with a significant burial of solvent-accessible surface area. The protein is an all-alpha protein composed of five helices: a four-helix bundle, and a short additional helix at the dimer interface. The protein is structurally similar to portions of the diiron-containing proteins, rubrerythrin and the Bacillus anthracis Dlp-2.

PubMed: 17001035
DOI: 10.1110/ps.062307706

実験手法

X-RAY DIFFRACTION (2 Å)