2GS0

NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the activation domain of p53

2GS0 の概要

• エントリーDOI: 10.2210/pdb2gs0/pdb
• NMR情報: BMRB: 6225
• 分子名称: RNA polymerase II transcription factor B subunit 1, Cellular tumor antigen p53 (2 entities in total)
• 機能のキーワード: p53, tfiih, tfb1, activation, transcription, ph domain
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast); 詳細
• 細胞内の位置: Nucleus: P32776; Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 18922.37

構造登録者

Di Lello, P.,Jones, T.N.,Nguyen, B.D.,Legault, P.,Omichinski, J.G. (登録日: 2006-04-25, 公開日: 2006-10-31, 最終更新日: 2024-05-29)

• 主引用文献: Di Lello, P.,Jenkins, L.M.,Jones, T.N.,Nguyen, B.D.,Hara, T.,Yamaguchi, H.,Dikeakos, J.D.,Appella, E.,Legault, P.,Omichinski, J.G.; Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53.; Mol.Cell, 22:731-740, 2006; PubMed: 16793543; DOI: 10.1016/j.molcel.2006.05.007

実験手法

SOLUTION NMR