2GNS

Design of specific peptide inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II phospholipase A2 and a designed pentapeptide Ala- Leu- Val- Tyr- Lys at 2.3 A resolution

Summary for 2GNS

• Entry DOI: 10.2210/pdb2gns/pdb
• Related: 1SV3 1TJ9
• Descriptor: Phospholipase A2 VRV-PL-VIIIa, ALVYK, SULFATE ION, ... (4 entities in total)
• Functional Keywords: peptide inhibitor, binding constant, hydrolase
• Biological source: Daboia russellii pulchella; More
• Cellular location: Secreted: P59071
• Total number of polymer chains: 2
• Total formula weight: 14319.57

Authors

Singh, N.,Sharma, S.,Somvanshi, R.K.,Dey, S.,Singh, T.P. (deposition date: 2006-04-11, release date: 2006-04-25, Last modification date: 2024-10-09)

• Primary citation: Singh, N.,Sharma, S.,Somvanshi, R.K.,Dey, S.,Singh, T.P.; Design of specific peptide inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II phospholipase A2 and a designed pentapeptide Ala - Leu - Val - Tyr - Lys at 2.3 A resolution; To be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)