2GKI
Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity
Summary for 2GKI
Entry DOI | 10.2210/pdb2gki/pdb |
Descriptor | nuclease (2 entities in total) |
Functional Keywords | anti-dna antibody, catalytic antibody, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 63008.63 |
Authors | Kim, Y.R.,Kim, J.S.,Lee, S.H.,Lee, W.R.,Sohn, J.N.,Chung, Y.C.,Shim, H.K.,Lee, S.C.,Kwon, M.H.,Kim, Y.S. (deposition date: 2006-04-02, release date: 2006-04-18, Last modification date: 2023-10-25) |
Primary citation | Kim, Y.R.,Kim, J.S.,Lee, S.H.,Lee, W.R.,Sohn, J.N.,Chung, Y.C.,Shim, H.K.,Lee, S.C.,Kwon, M.H.,Kim, Y.S. Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity. J.Biol.Chem., 281:15287-15295, 2006 Cited by PubMed: 16551636DOI: 10.1074/jbc.M600937200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.88 Å) |
Structure validation
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