2GKI

Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity

2GKI の概要

• エントリーDOI: 10.2210/pdb2gki/pdb
• 分子名称: nuclease (2 entities in total)
• 機能のキーワード: anti-dna antibody, catalytic antibody, immune system
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 63008.63

構造登録者

Kim, Y.R.,Kim, J.S.,Lee, S.H.,Lee, W.R.,Sohn, J.N.,Chung, Y.C.,Shim, H.K.,Lee, S.C.,Kwon, M.H.,Kim, Y.S. (登録日: 2006-04-02, 公開日: 2006-04-18, 最終更新日: 2023-10-25)

• 主引用文献: Kim, Y.R.,Kim, J.S.,Lee, S.H.,Lee, W.R.,Sohn, J.N.,Chung, Y.C.,Shim, H.K.,Lee, S.C.,Kwon, M.H.,Kim, Y.S.; Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity.; J.Biol.Chem., 281:15287-15295, 2006; PubMed: 16551636; DOI: 10.1074/jbc.M600937200

実験手法

X-RAY DIFFRACTION (2.88 Å)