2GD7

The Structure of the Cyclin T-binding domain of Hexim1 reveals the molecular basis for regulation of transcription elongation

2GD7 の概要

• エントリーDOI: 10.2210/pdb2gd7/pdb
• 分子名称: HEXIM1 protein (1 entity in total)
• 機能のキーワード: hexim1, transcription regulation, transcription elongation, positive transcription elongation factor-b, p-tefb nmr, structure determination, symmetric dimer, coiled coil, maq1, clp-1, edg1, transcription
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 25360.10

構造登録者

Dames, S.A. (登録日: 2006-03-15, 公開日: 2007-06-12, 最終更新日: 2024-05-29)

• 主引用文献: Dames, S.A.,Schonichen, A.,Schulte, A.,Barboric, M.,Peterlin, B.M.,Grzesiek, S.,Geyer, M.; Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb.; Proc.Natl.Acad.Sci.Usa, 104:14312-14317, 2007; PubMed: 17724342; DOI: 10.1073/pnas.0701848104

実験手法

SOLUTION NMR