2GD4

Crystal Structure of the Antithrombin-S195A Factor Xa-Pentasaccharide Complex

2GD4 の概要

• エントリーDOI: 10.2210/pdb2gd4/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900028
• 分子名称: Coagulation factor X, Stuart factor, Stuart-Prower factor, Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain, Coagulation factor, Stuart factor, Stuart-Prower factor, Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain, Antithrombin-III, ... (9 entities in total)
• 機能のキーワード: serpin, michaelis complex, hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 173130.35

構造登録者

Johnson, D.J.,Li, W.,Adams, T.E.,Huntington, J.A. (登録日: 2006-03-15, 公開日: 2006-05-09, 最終更新日: 2024-03-13)

• 主引用文献: Johnson, D.J.,Li, W.,Adams, T.E.,Huntington, J.A.; Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation.; Embo J., 25:2029-2037, 2006; PubMed: 16619025; DOI: 10.1038/sj.emboj.7601089

実験手法

X-RAY DIFFRACTION (3.3 Å)