Crystal structure of the human RhoC-GSP complex

Summary for 2GCP

Related2GCN 2GCO
DescriptorRho-related GTP-binding protein RhoC, MAGNESIUM ION, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... (5 entities in total)
Functional Keywordsgtp-binding protein, gtpase, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor; Cytoplasmic side (Potential) P08134
Total number of polymer chains1
Total molecular weight23461.19
Dias, S.M.G.,Cerione, R.A. (deposition date: 2006-03-14, release date: 2007-03-27, Last modification date: 2011-08-31)
Primary citation
Dias, S.M.G.,Cerione, R.A.
X-ray Crystal Structures Reveal Two Activated States for RhoC.
Biochemistry, 46:6547-6558, 2007
PubMed: 17497936 (PDB entries with the same primary citation)
DOI: 10.1021/bi700035p
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.227504.4%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2gcp
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Molmil generated image of 2gcp
rotated about x axis by 90°
Molmil generated image of 2gcp
rotated about y axis by 90°