2GCE
The 1,1-proton transfer reaction mechanism by alpha-methylacyl-CoA racemase is catalyzed by an aspartate/histidine pair and involves a smooth, methionine-rich surface for binding the fatty acyl moiety
2GCE の概要
エントリーDOI | 10.2210/pdb2gce/pdb |
関連するPDBエントリー | 1X74 2GCI 2GD0 2GD2 2GD6 |
分子名称 | probable alpha-methylacyl-CoA racemase MCR, (S)-IBUPROFENOYL-COENZYME A, (R)-IBUPROFENOYL-COENZYME A, ... (4 entities in total) |
機能のキーワード | alpha-methylacyl-coa racemase, racemase, coa transferase, proton transfer, coenzyme a, isomerase |
由来する生物種 | Mycobacterium tuberculosis |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 162545.67 |
構造登録者 | |
主引用文献 | Bhaumik, P.,Schmitz, W.,Hassinen, A.,Hiltunen, J.K.,Conzelmann, E.,Wierenga, R.K. The Catalysis of the 1,1-Proton Transfer by alpha-Methyl-acyl-CoA Racemase Is Coupled to a Movement of the Fatty Acyl Moiety Over a Hydrophobic, Methionine-rich Surface J.Mol.Biol., 367:1145-1161, 2007 Cited by PubMed: 17320106DOI: 10.1016/j.jmb.2007.01.062 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.85 Å) |
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