2G5B
Crystal Structure of the anti-Bax monoclonal antibody 6A7 and a Bax peptide.
Summary for 2G5B
| Entry DOI | 10.2210/pdb2g5b/pdb |
| Descriptor | 6A7 Fab Light Chain, 6A7 Fab Heavy Chain, Bax Peptide, ... (8 entities in total) |
| Functional Keywords | 6a7, bax, fab, antibody, fab-peptide complex, apoptosis |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 12 |
| Total formula weight | 197961.31 |
| Authors | Peyerl, F.W.,Dai, S.,Murphy, G.A.,Marrack, P.,Kappler, J.W. (deposition date: 2006-02-22, release date: 2006-07-25, Last modification date: 2020-07-29) |
| Primary citation | Peyerl, F.W.,Dai, S.,Murphy, G.A.,Crawford, F.,White, J.,Marrack, P.,Kappler, J.W. Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex. Cell Death Differ., 14:447-452, 2007 Cited by PubMed: 16946732DOI: 10.1038/sj.cdd.4402025 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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