2G0A
X-ray structure of mouse pyrimidine 5'-nucleotidase type 1 with lead(II) bound in active site
Summary for 2G0A
Entry DOI | 10.2210/pdb2g0a/pdb |
Related | 2BDU 2G06 2G07 2G08 2G09 |
Descriptor | Cytosolic 5'-nucleotidase III, LEAD (II) ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | uniprot q9d020, umph-1, cytosolic 5'-nucleotidase iii, pyrimidine 5'-nucleotidase 1, p5n-1, nt5c3 protein, aah38029, bc038029, mm.158936, lead poisoning, structural genomics functional follow-up study, protein structure initiative, psi, center for eukaryotic structural genomics, cesg, hydrolase |
Biological source | Mus musculus (house mouse) |
Cellular location | Cytoplasm (Potential): Q9D020 |
Total number of polymer chains | 2 |
Total formula weight | 69218.86 |
Authors | Bitto, E.,Bingman, C.A.,Wesenberg, G.E.,Phillips Jr., G.N.,Center for Eukaryotic Structural Genomics (CESG) (deposition date: 2006-02-11, release date: 2006-04-04, Last modification date: 2023-11-15) |
Primary citation | Bitto, E.,Bingman, C.A.,Wesenberg, G.E.,McCoy, J.G.,Phillips, G.N. Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning. J.Biol.Chem., 281:20521-20529, 2006 Cited by PubMed: 16672222DOI: 10.1074/jbc.M602000200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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