2FZ2

Structure of Turnip Yellow Mosaic Virus at 100 K

2FZ2 の概要

• エントリーDOI: 10.2210/pdb2fz2/pdb
• 関連するPDBエントリー: 1auy 1w39 2FZ1
• 分子名称: 5'-R(*CP*CP*C)-3', Coat protein (2 entities in total)
• 機能のキーワード: plant virus, coat protein, capsid protein, tymoviruses, tymv, rna, icosahedral virus, virus-rna complex, virus/rna
• 由来する生物種: Turnip yellow mosaic virus
• 細胞内の位置: Virion (Potential): P20125
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 61492.44

構造登録者

Larson, S.B.,Lucas, R.W.,McPherson, A. (登録日: 2006-02-08, 公開日: 2006-02-21, 最終更新日: 2023-08-30)

主引用文献

Larson, S.B.,Lucas, R.W.,Greenwood, A.,McPherson, A.
The RNA of turnip yellow mosaic virus exhibits icosahedral order.
Virology, 334:245-254, 2005

PubMed Abstract: Difference electron density maps, based on structure factor amplitudes and experimental phases from crystals of wild-type turnip yellow mosaic virus and those of empty capsids prepared by freeze-thawing, show a large portion of the encapsidated RNA to have an icosahedral distribution. Four unique segments of base-paired, double-helical RNA, one to two turns in length, lie between 33-A and 101-A radius and are organized about either 2-fold or 5-fold icosahedral axes. In addition, single-stranded loops of RNA invade the pentameric and hexameric capsomeres where they contact the interior capsid surface. The remaining RNA, not seen in electron density maps, must serve as connecting links between these secondary structural elements and is likely icosahedrally disordered. The distribution of RNA observed crystallographically appears to be in agreement with models based on biochemical data and secondary structural analyses.

PubMed: 15780874
DOI: 10.1016/j.virol.2005.01.036

実験手法

X-RAY DIFFRACTION (2.9 Å)