2FWW
human beta-tryptase II complexed with 4-piperidinebutyrate to make acylenzyme
Summary for 2FWW
Entry DOI | 10.2210/pdb2fww/pdb |
Related | 2FX4 2FX6 |
Descriptor | Tryptase beta-2, 4-PIPERIDINEBUTYRATE (3 entities in total) |
Functional Keywords | serine protease, proteinase, 29382, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P20231 |
Total number of polymer chains | 4 |
Total formula weight | 110586.65 |
Authors | Katz, B.A. (deposition date: 2006-02-03, release date: 2006-02-14, Last modification date: 2017-10-18) |
Primary citation | McGrath, M.E.,Sprengeler, P.A.,Hirschbein, B.,Somoza, J.R.,Lehoux, I.,Janc, J.W.,Gjerstad, E.,Graupe, M.,Estiarte, A.,Venkataramani, C.,Liu, Y.,Yee, R.,Ho, J.D.,Green, M.J.,Lee, C.-S.,Liu, L.,Tai, V.,Spencer, J.,Sperandio, D.,Katz, B.A. Structure-guided design of Peptide-based tryptase inhibitors. Biochemistry, 45:5964-5973, 2006 Cited by PubMed: 16681368DOI: 10.1021/bi060173m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
Download full validation report