2FVL

Crystal structure of human 3-alpha hydroxysteroid/dihydrodiol dehydrogenase (AKR1C4) complexed with NADP+

Summary for 2FVL

• Entry DOI: 10.2210/pdb2fvl/pdb
• Related: 1XF0
• Descriptor: Aldo-keto reductase family 1, member C4, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• Functional Keywords: chlordecone reductase, aldo-keto reductase, 3alpha-hsd1, dd4, structural genomics, structural genomics consortium, sgc, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 114100.01

Authors

Ugochukwu, E.,Smee, C.,Guo, K.,Lukacik, P.,Kavanagh, K.,Debreczeni, J.E.,von Delft, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2006-01-31, release date: 2006-02-21, Last modification date: 2023-10-25)

• Primary citation: Ugochukwu, E.,Smee, C.,Guo, K.,Lukacik, P.,Kavanagh, K.,Debreczeni, J.E.,von Delft, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Oppermann, U.; Crystal structure of human 3-alpha hydroxysteroid/dihydrodiol dehydrogenase (AKR1C4) complexed with NADP+; To be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)