2FU2

Crystal structure of protein SPy2152 from Streptococcus pyogenes

2FU2 の概要

• エントリーDOI: 10.2210/pdb2fu2/pdb
• 分子名称: Hypothetical protein SPy2152 (2 entities in total)
• 機能のキーワード: structural genomics, psi, protein structure initiative, midwest center for structural genomics, mcsg, unknown function
• 由来する生物種: Streptococcus pyogenes
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11468.67

構造登録者

Chang, C.,Cymborowski, M.,Otwinowski, Z.,Minor, W.,Lezondra, L.-E.,Clancy, S.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) (登録日: 2006-01-25, 公開日: 2006-03-07, 最終更新日: 2024-11-06)

主引用文献

Chang, C.,Coggill, P.,Bateman, A.,Finn, R.D.,Cymborowski, M.,Otwinowski, Z.,Minor, W.,Volkart, L.,Joachimiak, A.
The structure of pyogenecin immunity protein, a novel bacteriocin-like immunity protein from Streptococcus pyogenes.
Bmc Struct.Biol., 9:75-75, 2009

PubMed Abstract: Many Gram-positive lactic acid bacteria (LAB) produce anti-bacterial peptides and small proteins called bacteriocins, which enable them to compete against other bacteria in the environment. These peptides fall structurally into three different classes, I, II, III, with class IIa being pediocin-like single entities and class IIb being two-peptide bacteriocins. Self-protective cognate immunity proteins are usually co-transcribed with these toxins. Several examples of cognates for IIa have already been solved structurally. Streptococcus pyogenes, closely related to LAB, is one of the most common human pathogens, so knowledge of how it competes against other LAB species is likely to prove invaluable.

PubMed: 20017931
DOI: 10.1186/1472-6807-9-75

実験手法

X-RAY DIFFRACTION (2.15 Å)