2FQT

Crystal structure of B.subtilis LuxS in complex with (2S)-2-Amino-4-[(2R,3S)-2,3-dihydroxy-3-N-hydroxycarbamoyl-propylmercapto]butyric acid

Summary for 2FQT

• Entry DOI: 10.2210/pdb2fqt/pdb
• Related: 2FQO
• Descriptor: S-ribosylhomocysteine lyase, SULFATE ION, COBALT (II) ION, ... (5 entities in total)
• Functional Keywords: luxs, quorum sensing, lyase
• Biological source: Bacillus subtilis
• Total number of polymer chains: 1
• Total formula weight: 18257.58

Authors

Shen, G.,Rajan, R.,Zhu, J.,Bell, C.E.,Pei, D. (deposition date: 2006-01-18, release date: 2006-05-30, Last modification date: 2023-08-30)

• Primary citation: Shen, G.,Rajan, R.,Zhu, J.,Bell, C.E.,Pei, D.; Design and Synthesis of Substrate Analogue Inhibitors of S-Ribosylhomocysteinase (LuxS); J.Med.Chem., 49:3003-3011, 2006; PubMed: 16686542; DOI: 10.1021/jm060047g

Experimental method

X-RAY DIFFRACTION (1.79 Å)