2FQ6

Cystathionine beta-lyase (cbl) from escherichia coli in complex with n-hydrazinocarbonylmethyl-2-trifluoromethyl-benzamide

2FQ6 の概要

• エントリーDOI: 10.2210/pdb2fq6/pdb
• 分子名称: Cystathionine beta-lyase, PHOSPHORIC ACID MONO-(5-HYDROXY-6-METHYL-4-{[2-(2-TRIFLUOROMETHYL-BENZOYLAMINO)-ACETYL]-HYDRAZONOMETHYL}-PYRIDIN-3-YLMETHYL)ESTER (3 entities in total)
• 機能のキーワード: protein-inhibitor complex, plp cofactor covalently bound to p3f inhibitor, lyase
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm: P06721
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 91845.91

構造登録者

Junop, M.S. (登録日: 2006-01-17, 公開日: 2006-12-26, 最終更新日: 2023-08-30)

• 主引用文献: Ejim, L.J.,Blanchard, J.E.,Koteva, K.P.,Sumerfield, R.,Elowe, N.H.,Chechetto, J.D.,Brown, E.D.,Junop, M.S.,Wright, G.D.; Inhibitors of bacterial cystathionine beta-lyase: leads for new antimicrobial agents and probes of enzyme structure and function.; J.Med.Chem., 50:755-764, 2007; PubMed: 17300162; DOI: 10.1021/jm061132r

実験手法

X-RAY DIFFRACTION (1.78 Å)