2FMB
EIAV PROTEASE COMPLEXED WITH AN INHIBITOR LP-130
Summary for 2FMB
Entry DOI | 10.2210/pdb2fmb/pdb |
Descriptor | EQUINE INFECTIOUS ANEMIA VIRUS PROTEASE, 4-[2-(2-ACETYLAMINO-3-NAPHTALEN-1-YL-PROPIONYLAMINO)-4-METHYL-PENTANOYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL)-PROPYL]-AMIDE (3 entities in total) |
Functional Keywords | aspartic protease, retropepsin, retrovirus, eiav, horse |
Biological source | Equine infectious anemia virus |
Total number of polymer chains | 1 |
Total formula weight | 12187.24 |
Authors | Kervinen, J.,Lubkowski, J.,Zdanov, A.,Wlodawer, A.,Gustchina, A. (deposition date: 1998-07-13, release date: 1999-01-13, Last modification date: 2023-08-09) |
Primary citation | Kervinen, J.,Lubkowski, J.,Zdanov, A.,Bhatt, D.,Dunn, B.M.,Hui, K.Y.,Powell, D.J.,Kay, J.,Wlodawer, A.,Gustchina, A. Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV. Protein Sci., 7:2314-2323, 1998 Cited by PubMed: 9827997PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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