2FMB

EIAV PROTEASE COMPLEXED WITH AN INHIBITOR LP-130

2FMB の概要

• エントリーDOI: 10.2210/pdb2fmb/pdb
• 分子名称: EQUINE INFECTIOUS ANEMIA VIRUS PROTEASE, 4-[2-(2-ACETYLAMINO-3-NAPHTALEN-1-YL-PROPIONYLAMINO)-4-METHYL-PENTANOYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL)-PROPYL]-AMIDE (3 entities in total)
• 機能のキーワード: aspartic protease, retropepsin, retrovirus, eiav, horse
• 由来する生物種: Equine infectious anemia virus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 12187.24

構造登録者

Kervinen, J.,Lubkowski, J.,Zdanov, A.,Wlodawer, A.,Gustchina, A. (登録日: 1998-07-13, 公開日: 1999-01-13, 最終更新日: 2023-08-09)

• 主引用文献: Kervinen, J.,Lubkowski, J.,Zdanov, A.,Bhatt, D.,Dunn, B.M.,Hui, K.Y.,Powell, D.J.,Kay, J.,Wlodawer, A.,Gustchina, A.; Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV.; Protein Sci., 7:2314-2323, 1998; PubMed: 9827997

実験手法

X-RAY DIFFRACTION (1.8 Å)