2FM7

Evolution of Enzymatic Activity in the Tautomerase Superfamily: Mechanistic and Structural Consequences of the L8R Mutation in 4-Oxalocrotonate Tautomerase

Summary for 2FM7

Entry DOI	10.2210/pdb2fm7/pdb
Descriptor	4-Oxalocrotonate Tautomerase, CHLORIDE ION (3 entities in total)
Functional Keywords	4-oxalocrotonate; tautomerase; 4-ot; homo-hexamer; dehalogenase; mutant; l8r, transferase
Biological source	Pseudomonas putida
Total number of polymer chains	6
Total formula weight	40629.85
Authors	Almrud, J.J.,Hackert, M.L. (deposition date: 2006-01-08, release date: 2006-09-26, Last modification date: 2023-08-30)
Primary citation	Poelarends, G.J.,Almrud, J.J.,Serrano, H.,Darty, J.E.,Johnson, W.H.,Hackert, M.L.,Whitman, C.P. Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase Biochemistry, 45:7700-7708, 2006 Cited by PubMed: 16784221 DOI: 10.1021/bi0600603 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation