2FBB

Crystal Structure Analysis of Hexagonal Lysozyme

2FBB の概要

• エントリーDOI: 10.2210/pdb2fbb/pdb
• 分子名称: Lysozyme C, SODIUM ION, NITRATE ION, ... (4 entities in total)
• 機能のキーワード: hexagonal lysozyme, hydrolase
• 由来する生物種: Gallus gallus (chicken)
• 細胞内の位置: Secreted: P00698
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15438.19

構造登録者

Brinkmann, C.,Weiss, M.S.,Weckert, E. (登録日: 2005-12-09, 公開日: 2006-03-28, 最終更新日: 2024-10-16)

主引用文献

Brinkmann, C.,Weiss, M.S.,Weckert, E.
The structure of the hexagonal crystal form of hen egg-white lysozyme.
Acta Crystallogr.,Sect.D, 62:349-355, 2006

PubMed Abstract: The three-dimensional structure of hen egg-white lysozyme (HEWL) in a hexagonal crystal form has been determined and refined to 1.46 A resolution. This hexagonal crystal form crystallizes from a saturated sodium nitrate solution at pH 8.4. The crystals belong to space group P6(1)22, with unit-cell parameters a = b = 85.64, c = 67.93 A. A total of 165 water molecules, 16 nitrate ions and five sodium ions were located in the electron-density map. The hexagonal crystal form exhibits a higher solvent content and a higher degree of disorder than other crystal forms of lysozyme. The flexibility of the protein depends on the crystal packing, although some residue ranges are flexible in all native HEWL crystal forms.

PubMed: 16552135
DOI: 10.1107/S0907444906000825

実験手法

X-RAY DIFFRACTION (1.46 Å)