2F9R

Crystal structure of the inactive state of the Smase I, a sphingomyelinase D from Loxosceles laeta venom

Summary for 2F9R

Entry DOI	10.2210/pdb2f9r/pdb
Related	1XX1
Descriptor	Sphingomyelinase D 1, MAGNESIUM ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	sphingomyelinase d, catalytic activity, magnesium-binding site, inactive state, hydrolase
Biological source	Loxosceles laeta
Cellular location	Secreted: Q8I914
Total number of polymer chains	4
Total formula weight	129143.95
Authors	Murakami, M.T.,Gabdoulkhakov, A.,Fernandes-Pedrosa, M.F.,Betzel, C.,Tambourgi, D.V.,Arni, R.K. (deposition date: 2005-12-06, release date: 2006-06-27, Last modification date: 2023-08-30)
Primary citation	Murakami, M.T.,Gabdoulkhakov, A.,Fernandes-Pedrosa, M.F.,Tambourgi, D.V.,Arni, R.K. Structural basis for metal ion coordination and the catalytic mechanism of sphingomyelinases D. J.Biol.Chem., 280:13658-13664, 2005 Cited by PubMed: 15654080 DOI: 10.1074/jbc.M412437200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation