2F6Q

The crystal structure of human peroxisomal delta3, delta2 enoyl CoA isomerase (PECI)

Summary for 2F6Q

DescriptorPeroxisomal 3,2-trans-enoyl-CoA isomerase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
Functional Keywordsenoyl coa isomerase, peroxisomes, fatty acid metabolism, structural genomics, structural genomics consortium, sgc, isomerase
Biological sourceHomo sapiens (human)
Cellular locationIsoform 1: Mitochondrion (By similarity). Isoform 2: Peroxisome matrix O75521
Total number of polymer chains3
Total molecular weight94177.4
Authors
Primary citation
Turnbull, A.,Lukacik, P.,Shafqat, N.,Smee, C.,Berridge, G.,Guo, K.,von Delft, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Gileadi, O.,Oppermann, U.
The crystal structure of human peroxisomal delta3, delta2 enoyl CoA isomerase (PECI)
To be Published,
Experimental method
X-RAY DIFFRACTION (1.95 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25740.5%2.4%2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report