2F5B
CRYSTAL STRUCTURE OF FAB' FROM THE HIV-1 NEUTRALIZING ANTIBODY 2F5 IN COMPLEX WITH ITS GP41 EPITOPE
Summary for 2F5B
Entry DOI | 10.2210/pdb2f5b/pdb |
Descriptor | PROTEIN (ANTIBODY 2F5 (LIGHT CHAIN)), PROTEIN (ANTIBODY 2F5 (HEAVY CHAIN)), PROTEIN (GP41 EPITOPE), ... (4 entities in total) |
Functional Keywords | fab complex, hiv-1 neutralization, gp41, immunoglobulin |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 49168.17 |
Authors | Bryson, S.,Julien, J.P.,Hynes, R.C.,Pai, E.F. (deposition date: 1999-04-09, release date: 2003-07-08, Last modification date: 2023-08-23) |
Primary citation | Bryson, S.,Julien, J.P.,Hynes, R.C.,Pai, E.F. Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications. J.Virol., 83:11862-11875, 2009 Cited by PubMed: 19740978DOI: 10.1128/JVI.01604-09 PDB entries with the same primary citation |
Experimental method |
Structure validation
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