2F4O

The Mouse PNGase-HR23 Complex Reveals a Complete Remodulation of the Protein-Protein Interface Compared to its Yeast Orthologs

2F4O の概要

• エントリーDOI: 10.2210/pdb2f4o/pdb
• 関連するPDBエントリー: 2F4M
• 関連するBIRD辞書のPRD_ID: PRD_000338
• 分子名称: peptide N-glycanase, XP-C repair complementing complex 58 kDa protein, PHQ-VAL-ALA-ASP-CF0, ... (6 entities in total)
• 機能のキーワード: glycoproteins, ubiquitin-dependent protein degradation, nucleotide excision repair, peptide:n-glycanase, transglutaminase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Nucleus : P54728
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 42690.07

構造登録者

Zhao, G.,Zhou, X.,Wang, L.,Kisker, C.,Lennarz, W.J.,Schindelin, H. (登録日: 2005-11-23, 公開日: 2006-03-07, 最終更新日: 2023-08-23)

• 主引用文献: Zhao, G.,Zhou, X.,Wang, L.,Li, G.,Kisker, C.,Lennarz, W.J.,Schindelin, H.; Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.; J.Biol.Chem., 281:13751-13761, 2006; PubMed: 16500903; DOI: 10.1074/jbc.M600137200

実験手法

X-RAY DIFFRACTION (2.26 Å)