2F1Z

Crystal structure of HAUSP

Summary for 2F1Z

• Entry DOI: 10.2210/pdb2f1z/pdb
• Related: 2F1W 2F1X 2F1Y
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 7 (2 entities in total)
• Functional Keywords: hausp, usp7, ubp, deubiquitinating enzyme, substrate recognition, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q93009
• Total number of polymer chains: 2
• Total formula weight: 121065.54

Authors

Hu, M.,Gu, L.,Jeffrey, P.D.,Shi, Y. (deposition date: 2005-11-15, release date: 2006-02-07, Last modification date: 2023-08-23)

• Primary citation: Hu, M.,Gu, L.,Li, M.,Jeffrey, P.D.,Gu, W.,Shi, Y.; Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.; Plos Biol., 4:e27-e27, 2006; PubMed: 16402859; DOI: 10.1371/journal.pbio.0040027

Experimental method

X-RAY DIFFRACTION (3.2 Å)