2F13

Crystal Structure of the Human Sialidase Neu2 in Complex with 2',3'- dihydroxypropyl ether mimetic Inhibitor

2F13 の概要

• エントリーDOI: 10.2210/pdb2f13/pdb
• 関連するPDBエントリー: 1SNT 1SO7 1VCU 2F0Z 2F10 2F11 2F12 2F24 2F25 2F26 2F27 2F28 2F29
• 分子名称: Sialidase 2, PHOSPHATE ION, (2R)-2,3-dihydroxypropyl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid, ... (4 entities in total)
• 機能のキーワード: sialidase, neuraminidase, influenza virus, drug design, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42805.82

構造登録者

Chavas, L.M.G.,Kato, R.,Mann, M.C.,Thomson, R.J.,Dyason, J.C.,von Itzstein, M.,Fusi, P.,Tringali, C.,Venerando, B.,Tettamanti, G.,Monti, E.,Wakatsuki, S. (登録日: 2005-11-14, 公開日: 2006-11-21, 最終更新日: 2023-10-25)

• 主引用文献: Chavas, L.M.G.,Kato, R.,Mann, M.C.,Thomson, R.J.,Dyason, J.C.,von Itzstein, M.,Fusi, P.,Tringali, C.,Venerando, B.,Tettamanti, G.,Monti, E.,Wakatsuki, S.; Crystal Structure of the Human Sialidase Neu2 in Complex with 2',3'- dihydroxypropyl ether mimetic Inhibitor; To be Published,

実験手法

X-RAY DIFFRACTION (2.26 Å)