2F0Y

Crystal Structure Of Human Protein Farnesyltransferase Complexed With Farnesyl Diphosphate and hydantoin derivative

Summary for 2F0Y

• Entry DOI: 10.2210/pdb2f0y/pdb
• Descriptor: Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ... (6 entities in total)
• Functional Keywords: farnesyltransferase, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 94193.11

Authors

Kim, K.H.,Lee, J.,Kim, J. (deposition date: 2005-11-14, release date: 2006-11-14, Last modification date: 2024-03-13)

• Primary citation: Lee, J.,Kim, J.,Koh, J.S.,Chung, H.H.,Ro, S.,Kim, K.H.; hydantoin derivatives as Non-pepridic inhibitors of Ras Farnesyl transferase; To be published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)