2EZT

Pyruvate oxidase variant F479W in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate

Summary for 2EZT

Entry DOI	10.2210/pdb2ezt/pdb
Related	1POW 1POX 1Y9D 2EZ4 2EZ8 2EZ9 2EZU
Descriptor	Pyruvate oxidase, MAGNESIUM ION, PHOSPHATE ION, ... (8 entities in total)
Functional Keywords	tpp enzyme, reaction intermediate, oxidoreductase
Biological source	Lactobacillus plantarum
Total number of polymer chains	2
Total formula weight	135460.15
Authors	Wille, G.,Meyer, D.,Steinmetz, A.,Hinze, E.,Golbik, R.,Tittmann, K. (deposition date: 2005-11-10, release date: 2006-04-25, Last modification date: 2023-11-15)
Primary citation	Wille, G.,Meyer, D.,Steinmetz, A.,Hinze, E.,Golbik, R.,Tittmann, K. The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography. Nat.Chem.Biol., 2:324-328, 2006 Cited by PubMed: 16680160 DOI: 10.1038/nchembio788 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation