2EU3
Human Carbonic anhydrase II in complex with novel inhibitors
Summary for 2EU3
Entry DOI | 10.2210/pdb2eu3/pdb |
Related | 2EU2 |
Descriptor | Carbonic anhydrase 2, ZINC ION, 1-(5-AMINO-1,3,4-THIADIAZOL-2-YL)-1,1-DIFLUOROMETHANESULFONAMIDE, ... (4 entities in total) |
Functional Keywords | carbonic anhydrase ii proton transfer inhibitor, lyase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 29584.69 |
Authors | Fisher, S.Z.,Govindasamy, L.,Boyle, N.,Agbandje-McKenna, M.,Silverman, D.N.,Blackburn, G.M.,McKenna, R. (deposition date: 2005-10-28, release date: 2006-07-11, Last modification date: 2023-08-23) |
Primary citation | Fisher, S.Z.,Govindasamy, L.,Boyle, N.,Agbandje-McKenna, M.,Silverman, D.N.,Blackburn, G.M.,McKenna, R. X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes. Acta Crystallogr.,Sect.F, 62:618-622, 2006 Cited by PubMed: 16820676DOI: 10.1107/S1744309106020446 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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