2ET8

Complex Between Neamine and the 16S-RRNA A-Site

Summary for 2ET8

• Entry DOI: 10.2210/pdb2et8/pdb
• Related: 1J7T
• Descriptor: 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside (3 entities in total)
• Functional Keywords: rna-aminoglycoside interactions, a site, uou pairs, aa bulges, rna
• Total number of polymer chains: 2
• Total formula weight: 14418.88

Authors

Westhof, E. (deposition date: 2005-10-27, release date: 2005-12-13, Last modification date: 2023-08-23)

• Primary citation: Francois, B.,Russell, R.J.,Murray, J.B.,Aboul-ela, F.,Masquida, B.,Vicens, Q.,Westhof, E.; Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding.; Nucleic Acids Res., 33:5677-5690, 2005; PubMed: 16214802; DOI: 10.1093/nar/gki862

Experimental method

X-RAY DIFFRACTION (2.5 Å)