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2ET3

Complex Between Gentamicin C1A and the 16S-RRNA A-Site

Summary for 2ET3
Entry DOI10.2210/pdb2et3/pdb
Related1J7T 1MWL
Descriptor5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL (3 entities in total)
Functional Keywordsrna-aminoglycoside interactions, a site, uou pairs, aa bulges, rna
Total number of polymer chains2
Total formula weight14995.60
Authors
Westhof, E. (deposition date: 2005-10-27, release date: 2005-12-13, Last modification date: 2023-08-23)
Primary citationFrancois, B.,Russell, R.J.,Murray, J.B.,Aboul-ela, F.,Masquida, B.,Vicens, Q.,Westhof, E.
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding.
Nucleic Acids Res., 33:5677-5690, 2005
Cited by
PubMed: 16214802
DOI: 10.1093/nar/gki862
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

217705

건을2024-03-27부터공개중

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