2ET3

Complex Between Gentamicin C1A and the 16S-RRNA A-Site

2ET3 の概要

• エントリーDOI: 10.2210/pdb2et3/pdb
• 関連するPDBエントリー: 1J7T 1MWL
• 分子名称: 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL (3 entities in total)
• 機能のキーワード: rna-aminoglycoside interactions, a site, uou pairs, aa bulges, rna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 14995.60

構造登録者

Westhof, E. (登録日: 2005-10-27, 公開日: 2005-12-13, 最終更新日: 2023-08-23)

• 主引用文献: Francois, B.,Russell, R.J.,Murray, J.B.,Aboul-ela, F.,Masquida, B.,Vicens, Q.,Westhof, E.; Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding.; Nucleic Acids Res., 33:5677-5690, 2005; PubMed: 16214802; DOI: 10.1093/nar/gki862

実験手法

X-RAY DIFFRACTION (2.8 Å)