2ET0

The structure of a three-way DNA junction in complex with a metallo-supramolecular helicate reveals a new target for drugs

Summary for 2ET0

• Entry DOI: 10.2210/pdb2et0/pdb
• Descriptor: 5'-D(*CP*GP*TP*AP*CP*G)-3', FE (II) ION, N-[(1E)-PYRIDIN-2-YLMETHYLENE]-N-[4-(4-{[(1E)-PYRIDIN-2-YLMETHYLENE]AMINO}BENZYL)PHENYL]AMINE, ... (4 entities in total)
• Functional Keywords: drug-dna complex, 3-way junction, dna structure recognition, dna
• Total number of polymer chains: 2
• Total formula weight: 5835.77

Authors

Oleksi, A.,Blanco, A.G.,Boer, R.,Uson, I.,Aymami, J.,Coll, M. (deposition date: 2005-10-27, release date: 2006-03-14, Last modification date: 2024-02-14)

• Primary citation: Oleksi, A.,Blanco, A.G.,Boer, R.,Uson, I.,Aymami, J.,Rodger, A.,Hannon, M.J.,Coll, M.; Molecular Recognition of a Three-Way DNA Junction by a Metallosupramolecular Helicate; ANGEW.CHEM.INT.ED.ENGL., 45:1227-1231, 2006; PubMed: 16463312; DOI: 10.1002/anie.200503822

Experimental method

X-RAY DIFFRACTION (1.7 Å)