2ESJ

Complex between Lividomycin A and the 16S-Rrna A Site

Summary for 2ESJ

• Entry DOI: 10.2210/pdb2esj/pdb
• Related: 1J7T 2BE0 2BEE 2ESI
• Descriptor: 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R ,5S,6R)-3-AMINO-5-HYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-4-HYDROXY-2-(HYDROXYMET HYL)-TETRAHYDROFURAN-3-YLOXY)-4-HYDROXY-TETRAHYDRO-2H-PYRAN-3-YLOXY)-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL (3 entities in total)
• Functional Keywords: rna-aminoglycoside interactions, a site, uou pairs, aa bulges, rna
• Total number of polymer chains: 2
• Total formula weight: 15620.06

Authors

Westhof, E. (deposition date: 2005-10-26, release date: 2005-12-20, Last modification date: 2024-02-14)

• Primary citation: Francois, B.,Russel, R.J.M.,Murray, J.B.,Aboul-ela, F.,Masquida, B.,Vicens, Q.,Westhof, E.; Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding; Nucleic Acids Res., 33:5677-5690, 2005; PubMed: 16214802; DOI: 10.1093/nar/gki862

Experimental method

X-RAY DIFFRACTION (2.2 Å)