2EI7

FACTOR XA IN COMPLEX WITH THE INHIBITOR trans-N1-[(5-Chloroindol-2-yl)carbonyl]-N2-[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]-1,2-cyclohexanediamine

Summary for 2EI7

• Entry DOI: 10.2210/pdb2ei7/pdb
• Related: 1v3x 1wu1 2EI6 2EI8 2d1j
• Descriptor: Coagulation factor X, heavy chain, Coagulation factor X, light chain, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P00742 P00742
• Total number of polymer chains: 2
• Total formula weight: 32745.69

Authors

Suzuki, M. (deposition date: 2007-03-12, release date: 2008-03-18, Last modification date: 2024-10-23)

• Primary citation: Nagata, T.,Yoshino, T.,Haginoya, N.,Yoshikawa, K.,Isobe, Y.,Furugohri, T.,Kanno, H.; Cycloalkanediamine derivatives as novel blood coagulation factor Xa inhibitors; To be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)