2EAR

P21 crystal of the SR CA2+-ATPase with bound TG

2EAR の概要

• エントリーDOI: 10.2210/pdb2ear/pdb
• 関連するPDBエントリー: 1WPG 2AGV 2EAS 2EAT 2EAU
• 分子名称: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER (2 entities in total)
• 機能のキーワード: membrane protein, p-type atpase, had fold, ca2+, ion pump, hydrolase
• 由来する生物種: Oryctolagus cuniculus (rabbit)
• 細胞内の位置: Endoplasmic reticulum membrane; Multi-pass membrane protein: P04191
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 110279.37

構造登録者

Takahashi, M.,Kondou, Y.,Toyoshima, C. (登録日: 2007-02-02, 公開日: 2007-03-27, 最終更新日: 2023-10-25)

• 主引用文献: Takahashi, M.,Kondou, Y.,Toyoshima, C.; Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors; Proc.Natl.Acad.Sci.Usa, 104:5800-5805, 2007; PubMed: 17389383; DOI: 10.1073/pnas.0700979104

実験手法

X-RAY DIFFRACTION (3.1 Å)